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As we speak's drug pricing tendencies, particularly within the specialty drug sector, significantly threaten the affordability of health care within the United States. Coverage factors, akin to drug reimbursement and cost-sharing insurance policies (such as copays and coinsurance), Medicare and Medicaid reimbursement insurance policies, and state laws prohibiting restrictions on drug prescribing. Medicare expenditures account for a 29% share of all spending on retail prescription drugs, and in 2015, the Half D program spent $137.4 billion on drugs ( 6 ). Ten medication accounted for 21% of Half D spending in 2015, together with Harvoni (ledipasvir-sofosbuvir) for hepatitis C, Lantus (insulin glargine injection) for diabetes, Crestor (rosuvastatin calcium) for top ldl cholesterol, Nexium (esomeprazole magnesium) for acid reflux disorder, and Humira (adalimumab) for rheumatoid arthritis ( 7 ).


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