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Trying to cram extra fats (with glucose for the glycerol) in to those adipocytes is sort of unattainable, a scenario worse than that with these half empty adipocytes after IH or crystal meth publicity. Giving some "space" inside an adipocyte allows the insulin sensitising effect of PUFA oxidation to point out, certainly whereas fasting and lipolysis is the correct state to be in The missing piece of information might be FFAs. Just to make clear: Acute exposure of freshly remoted adipocytes to trans-oleic acid causes fats release, decreased glucose uptake and decreased glucose incorporation in to lipids. 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