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Is mirtazapine an SSRI or SNRI? It is relatively easy to combine with other antidepressants, the venlafaxine + mirtazapine combination has been called "California Rocket Fuel". Since it has no activity on monoamine reuptake it has a complementary mechanism of action with SSRIs and SNRIs. Mirtazapine is approved only for depression.
Is mirtazapine a good antidepressant? Mirtazapine is a newer antidepressant that exhibits both noradrenergic and serotonergic activity. It is at least as effective as the older antidepressants for treating mild to severe depression. Mirtazapine is also a good choice in depressed patients with significant anxiety or insomnia.
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