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What is the first sign of kidney failure? Signs and symptoms of acute kidney failure may include: Decreased urine output, although occasionally urine output remains normal. Fluid retention, causing swelling in your legs, ankles or feet. Shortness of breath.
Can kidneys recover from damage? "If tubules are damaged they can be repaired but if the damage is severe enough the nephron may be destroyed. Unfortunately the kidney can regenerate and recover, but the kidney cannot make new nephrons, and in that context, its regeneration is limited."
How do ACE inhibitors affect the kidneys? In conditions in which glomerular filtration is critically dependent on angiotensin II-mediated efferent vascular tone (such as a post-stenotic kidney, or patients with heart failure and severe depletion of circulating volume), ACE inhibition can induce acute renal failure, which is reversible after withdrawal of the
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