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Does Xanax help with restless leg syndrome? Restoril, or temazepam, Xanax, or alprazolam, and Klonopin, or clonazepam, are examples. Dopaminergic agents: These medications raise the levels of dopamine, a neurotransmitter, in the brain. They can treat the unpleasant leg sensations associated with RLS. Opiates: Treat pain and can relieve RLS symptoms.



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