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When should mestinon be taken? You should take the medicine so that it can work when your muscles are needed most. For example when you get up and about 30 to 60 minutes before a meal. Never take more than the dose prescribed by your consultant neurologist.
How does mestinon work? In most people with myasthenia gravis, the immune system blocks or damages these acetylcholine receptors. The acetylcholine cannot then attach to the receptor and so the muscle is less able to tighten. Pyridostigmine works by slowing the breakdown of acetylcholine when it is released from nerve endings.
Does prednisone help myasthenia gravis? The most commonly used immunosuppressive agent for the treatment of MG is prednisone. Observational studies, clinical experience, and limited controlled trials suggest that prednisone usage leads to remission or marked improvement in 70% to 80% of patients with ocular or generalized MG.
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