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Can you build a tolerance to amitriptyline? May cause drowsiness and affect a person's ability to drive or operate machinery; some people may develop tolerance to this effect. Risk of heart-related effects, muscle rigidity, tremor, seizures, increased sensitivity to light, weight gain or loss, hair loss, skin rash, and edema.
Does savella work immediately? Savella isn't a pain pill; it doesn't work instantly. The second dose should be taken before 2 p.m. Unfortunately, doctors also aren't telling patients that Savella is an SNRI so it SHOULD NOT be taken w/ other antidepressants or it'll make you sick (serotonin syndrome).
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