Self‐monitoring Cognitive Performance During Sleep Deprivation: Effects Of Modafinil D‐amphetamine And Placebo

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In 2005, Teva and Cephalon settled patent disputes relating to Provigil - which is also known as Modafinil in the US and UK. As part of that deal, Teva agreed not to sell its generic version of Provigil in the EU as well as Iceland, Liechtenstein, and Norway before Oct. 2012, the EU's antitrust regulators claim. On December 22, 2004 Cephalon Inc. has asked the FDA to approve a version of its narcolepsy drug Provigil to be used to treat children with attention deficit hyperactivity disorder.


The US Federal Trade Association filed a lawsuit against Cephalon in 2008, alleging the company paid off potential competitors to keep a cheaper version Provigil off the market. The European Commission is now investigating whether that agreement broke EU antitrust regulations and had the "object or effect" of keeping generic Provigil out of the European market. But he's concerned that memory enhancement drugs might have you remember things you really don't want to remember.


In this study, the overall main effect of modafinil on the planned primary outcome (weekly% of cocaine non-use days) was not significant. This decreased cocaine use by about 1 dose - they were dosing 4to 6 time. If all other things were equal, an imbalance in disease severity across treatment groups would be expected to obscure any medication effect, and cause a bias toward a null result.


Modafinil is a cognitive enhancer first and foremost, and while it does have some euphoric effect, its so much more than a party powder. It means that Modafinil isn’t affecting the quality or quantity of my sleep (at least, not nearly as much as Adderall had been). Researchers from the University of Delaware and Drexel University College of Medicine reviewed the latest research on the effects of medications like Ritalin and Provigil on the juvenile brain and discovered smart drug use is certainly not benign. While amphetamine (Adderall) and methylphenidate (Ritalin) have been the norm in addressing attention deficit disorders, more and more individuals are raising concerns about the high risk of side effects associated with these drugs.

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